I have been admiring the comic depictions of Bill Schmalfeldt, liberal pundit (and serial harrasser) over at Kimberlin Unmasked. I believe the artist achieves these excellent graphic effects using filters and layers in Photoshop. I like the pixelated effects and the paper-like textures, resembling a comic book page. I am experimenting to develop some of these effects on my own. I'm not there yet, but am having fun trying.
Here is a photo of Bill Schmalfeldt, rendered into a comic book depiction, using Photoshop. It was just for fun, but use it however you may wish.